Peer-Reviewed Publications



Conference Proceedings

Peer-Reviewed Publications


46. Boazak EM, Greene Jr VK,  Auguste DT.  The effect of heterobifunctional crosslinkers on HEMA hydrogel modulus and toughness. PloS one. 2019 May 9;14(5):e0215895.
45. Kim B, Pena CD,  Auguste DT.  Targeted lipid nanoemulsions encapsulating epigenetic drugs exhibit selective cytotoxicity on CDH1-/FOXM1+ triple negative breast cancer cells. Molecular pharmaceutics. 2019 Mar 18.
44. Guo P, Yang J, Liu D, Huang L, Fell G, Huang J, Moses MA,  Auguste DT.  Dual complementary liposomes inhibit triple-negative breast tumor progression and metastasis. Science advances. 2019 Mar 1;5(3):eaav5010.


43. Large DE, Soucy JR, Hebert, J, Auguste DT. Advances in receptor-mediated, tumor-targeted drug delivery. Advanced Therapeutics. 2018 Sept; 1-27.
42. Liu D, Auguste DT. Peptide density targets and impedes triple negative breast cancer metastasis. Nature Communications. 2018 Jul; 9:2612.
41. Guo P, Wang B, Liu D, Yang J, Subramanyam K, McCarthy C, Hebert J, Moses M, Auguste DT. Using atomic force microscopy to predict tumor specificity of ICAM1 antibody-directed nanomedicines. Nano Letters. 2018 April; 18:2254-2262.
40. Boazak E, Auguste DT. Trachea mechanics for tissue engineering design. ACS Biomaterials Science and Engineering. 2018 Feb;4:1272-1284.
39. Guo P, Liu D, Subramanyam K, Wang B, Yang J, Huang J, Auguste DT, Moses MA. Nanoparticle elasticity directs tumor uptake. Nature Communications. 2018 Jan; 9:130


38. Boazak E, Benson J, Auguste DT. R and Z-axis patterned scaffolds mimic tracheal circumferential compliance and longitudinal extensibility. ACS Biomaterials Science and Engineering. 2017 Nov; 3:3222–3229.
37. Tao Y, Li M, Kim B, Auguste DTIncorporating gold nanoclusters and target-directed liposomes as a synergistic amplified colorimetric sensor for HER2-positive breast cancer cell detection. Theranostics. 2017 Feb 8;7(4):899-911. 
36. Guo P, Yang J, Bielenberg DR, Dillon D, Zurakowski D, Moses MA, Auguste DTA quantitative method for screening and identifying molecular targets for nano medicine. J Control Release. 2017 Mar 22. pii: S0168-3659(17)30141-4.
35. Tao Y, Li M, Auguste DTPattern-based sensing of triple negative breast cancer cells with dual-ligand cofunctionalized gold nano clusters. Biomaterials. 2017 Feb;116:21-33. 


34. Veneti E, Tu RS, Auguste DT. RGD-Targeted Liposome Binding and Uptake on Breast Cancer Cells Is Dependent on Elastin Linker Secondary Structure. Bioconjug Chem. 2016 Aug 17;27(8):1813-21.
33. Yu T, Auguste DT. Array-based identification of triple-negative breast cancer cells using fluorescent nanodot-graphene oxide complexes. Biosensors and Bioelectronics. Accepted.
32. Mansfield L, Greene V, Auguste DT. Patterned, tubular scaffolds mimic longitudinal and radial mechanics of the neonatal trachea. Acta Biomaterialia. 2016 Mar;33:176–182.
31. Guo P, Yang J, Jia D, Moses MA, Auguste DT. ICAM-1-Targeted, Lcn2 siRNA-Encapsulating Liposomes are Potent Anti-angiogenic Agents for Triple Negative Breast Cancer, Theranostics. 2016 Jan;6(1):1-13.


30. Almeda D, Wang B, Auguste DT. Minimizing antibody surface density on liposomes while sustaining cytokine-activated EC targeting. Biomaterials. 2015 Feb;41:37-44.
29. Liu D, Auguste DT, Cancer targeted therapeutics: From molecules to drug delivery vehicles, J. Control. Release 2015 Dec 10;219:632-643.
28. Ho TT, You JO, Auguste DT. siRNA delivery impedes the temporal expression of cytokine-activated VCAM1 on endothelial cells. Ann Biomed Eng. 2015 Jun 23.
27. Wang B, Guo P, Auguste DT. Mapping the CXCR4 receptor on breast cancer cells. Biomaterials. 2015 Jul;57:161–8. (pdf)
26. You J-O, Rafat M, Almeda D, Maldonado N, Guo P, Nabzdyk CS, Chun M, LoGerfo FW, Hutchinson JW, Pradhan-Nabzdyk LK, Auguste DT. pH-responsive scaffolds generate a pro-healing response. Biomaterials. 2015 Jul; 57:22-32. (pdf)


25. Guo P, Huang J, Wang L, Jia D, Yang J, Dillon DA, Zurakowski D, Mao H, Moses MA, Auguste DT. ICAM-1 as a molecular target for triple negative breast cancer. Proc Natl Acad Sci USA. 2014 Oct 14;111(41):14710-5.
24. Guo P, You J-O, Yang J, Jia D, Moses MA, Auguste DT. Inhibiting metastatic breast cancer cell migration via the synergy of targeted, pH-triggered siRNA delivery and chemokine axis blockade. Mol Pharm. 2014 Mar 3;11(3):755–65.


23. You J-O, Guo P, Auguste DT. A drug-delivery vehicle combining the targeting and thermal ablation of HER2+ breast-cancer cells with triggered drug release. Angew Chem Int Ed Engl. 2013 Apr 8;52(15):4141–6.


22. Guo P, You J-O, Yang J, Moses MA, Auguste DT. Using breast cancer cell CXCR4 surface expression to predict liposome binding and cytotoxicity. Biomaterials. 2012 Nov; 33(32):8104–10.
21. Horton RE, Auguste DT. Synergistic effects of hypoxia and extracellular matrix cues in cardiomyogenesis. Biomaterials. 2012 Sep;33(27):6313–9.
20. Rafat M, Rotenstein L, Hu J, Auguste DT. Engineered endothelial cell adhesion via VCAM1 and E-selectin antibody-presenting alginate hydrogels. Acta Biomaterialia 2012; 8(7): 2697-2703; published online, DOI: 10.1016/j.actbio.2012.04.010.
19. Rafat M, Rotenstein L, You J, Auguste DT. Dual functionalized PVA hydrogels that adhere endothelial cells synergistically. Biomaterials 2012; 33: 3880-3886; published online, DOI: 10.1016/j.biomaterials.2012.02.017. (pdf)
18. Hu Y, You J, Auguste DT, Suo Z, Vlassak J. Indentation: A simple, nondestructive method for characterizing the mechanical and transport properties of ff pH-sensitive hydrogels, Journal of Materials Research 2012; 27(1): 152-160. (pdf)


17. Gunawan R, Almeda D, Auguste DT. Complementary targeting of liposome to IL-1α and TNF-α activated endothelial cells via the transient expression of VCAM1 and E-selectin, Biomaterials 2011; 32: 9848-9858. (pdf)
16. You J, Rafat M, and Auguste DT. Crosslinked, heterogeneous colloidosomes exhibit pH-induced morphogenesis. Langmuir 2011; 27(18): 11282-11286; published online, DOI: 10.1021/la202430m. (pdf)
15. You J, Rafat M, Ye GJC, Auguste DT. Nanoengineering the heart: Conductive scaffolds enhance connexin 43 expression, Nano Letters 2011 Sep 14; 11(9): 3643-8; published online, DOI: 10.1021/nl201514a. (pdf)


14.You J, Almeda D, Ye GJC, Auguste DT.  Bioresponsive matrices in drug delivery. Journal of Biological Engineering 2010; 4:15.  (pdf)
13. Gunawan R, Auguste DT.  Immunoliposomes that target endothelium in vitro are dependent on lipid raft formation.  Molecular Pharmaceutics 2010; 7(5):1569-1575. (pdf)
12.You J, Auguste DT.  The effect of swelling and cationic character on gene transfection by pH-sensitive nanocarriers.  Biomaterials 2010; 31(26):6859-6866. (pdf)
11. You J, Auguste DT.  Conductive, physiologically responsive hydrogels.  Langmuir 2010; 26(7):4607-4612.  (pdf)
10. Gunawan R, Auguste DT.  The role of antibody synergy and membrane fluidity in the vascular targeting of immunoliposomes.  Biomaterials 2010; 31(5):900-907. (pdf)


9.You J, Auguste DT.  Nanocarrier cross-linking density and pH sensitivity regulate intracellular gene transfer.  Nano Letters 2009; 9(12):4467-4473.  Highlighted in MRS Bulletin 2010; 35.  (pdf)
8.Horton R, Millman J, Colton C, Auguste DT.  Engineering microenvironments for embryonic stem cell differentiation to cardiomyocytes.  Regenerative Medicine 2009; 4(5):721-732. (pdf)
7.Rafat M, Raad D, Rowat A, Auguste DT.  Fabrication of reversibly adhesive fluidic devices using magnetism.  Lab on a Chip 2009; 9(20):3016-3019. (pdf)


6.Sachlos E, Auguste DT.  Embryoid body morphology influences diffusive transport of inductive biochemicals: A strategy for stem cell differentiation. Leading Opinion Paper, Biomaterials 2008; 29(34):4471-4480. (pdf)
5.You J, Auguste DT.  Feedback-regulated paclitaxel delivery based on poly(N,N-dimethylaminoethyl methacrylate-co-2-hydroxyethyl methacrylate) nanoparticles.  Biomaterials 2008; 29(12):1950-1957. (pdf)
4.Auguste DT, Furman K, Wong A, Fuller J, Armes S, Deming T, Langer R. Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes enhances RNAi delivery.  Journal of Controlled Release 2008; 130:266-274. (pdf)
3.Auguste DT, Kirkwood J, Kohn J, Fuller GG, Prud'homme RK.  Surface rheology of hydrophobically-modified PEG polymers associating with a phospholipid monolayer at the air-water interface.  Langmuir 2008; 24(8):4056-4064. (pdf)


2.Auguste DT, Armes S, Brzezinska K, Deming T, Kohn J, Prud’homme RK.  pH-triggered release of protective poly(ethylene glycol)-b–polycation copolymers from liposomes.  Biomaterials 2006; 27:2599-2608. (pdf)
1.Auguste DT, Prud’homme RK, Ahl PL, Meers P, Kohn J. Association of hydrophobically-modified poly(ethylene glycol) with fusogenic liposomes. Biochimica et Biophysica Acta (BBA) 2003; 1616:184-195. (pdf)



1.Auguste DT, Satterstrom FK, Rafat M, You J, "Emerging technologies in nanomedicine," Nanobiomaterials Handbook, CRC Press, 2011.
2.Luo Y, Engelmayer G, Auguste DT, Ferreira L, Karp JM, Saigal R, Langer R.  Three-dimensional scaffolds, in Principles of Tissue Engineering, 3rd Ed., Lanza, R., Langer, R., and J. Vacanti (Eds.), Elsevier, 2007.
3.Auguste DT, Prud’homme RK, Ahl PL, Meers P, Kohn J.  Polymer-protected liposomes: association of hydrophobically-modified PEG with liposomes. (p. 95-120) in Polymeric Drug Delivery Volume I -Particulate Polymeric Matrices and Drug Particle Engineering, Svenson, S. (Ed.), ACS Symposium Series, Vol. 924, American Chemical Society, 2004.



1.Feedback-regulated materials including ph-triggered particles. U.S. Provisional Patent Application No.: 61/062,387. Filed January 25, 2008.


Conference Proceedings